Dr. Ravi Prabhakar More (Ph.D. Bioinformatics)
I am currently working as a Research Associate on the project "The NeuralNET: Research to impact diagnosis, mechanistic understanding and treatment of children's brain and mental health disorders" at the Department of Paediatrics, University of Cambridge, UK. My research interests focus on bioinformatic methods applied to biomedical sciences, particularly on developing cloud-based approaches for variants and gene prioritization to better understand the functional impact of genomic variations in rare disorders in critically ill children patients.
Prior to this, I worked as a Bioinformatics Research Associate on the "Investigating autism using genetics and epigenetics" (IMAGE) study at the Autism Research Centre (ARC), University of Cambridge, UK. My primary responsibilities were to conduct rare variant analysis of whole-genome sequencing (WGS) data of autism multiplex families using bioinformatic pipelines on High-Performance Computing (HPC) cluster platforms. Our team conducted whole-genome sequencing of 21 highly multiplex autism families to prioritize genes associated with autism, and as a shared first and corresponding author, our work was published in the prestigious "Nature Molecular Psychiatry" journal.
Before joining the University of Cambridge, I worked on the Accelerator program for Discovery in Brain disorders using Stem cells (ADBS) at TIFR-National Centre for Biological Sciences (NCBS), where I developed the GenomicsQC pipeline to assess cell line samples and analyzed whole-genome and exome sequence data for multiplex families with severe mental illness. Prior to this, I worked on an Insect Transcriptomics project and did DNA Barcoding studies of insect pests.
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I received my Ph.D. in Bioinformatics from NEERI and SRTM University Nanded, India. My doctoral thesis focused on developing software for taxonomic classification of bacteria and plants using pattern-based signatures.
I've authored 20 research articles published in well-reputed peer-reviewed international journals and was the editor of 'Soft Computing for Biological Systems' by Springer publications. I've also presented posters at several international conferences.
I'm a recipient of the award for outstanding project personnel at CSIR-NEERI, Nagpur India, and was an International Intern at NIBB Institute, Japan.